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Treatment Guide

Xeomin: The “Naked” Neuromodulator.

Xeomin contains only the active botulinum toxin, without the accessory proteins found in Botox and Dysport — a detail some patients specifically look for.

Reviewed by Dr. Justin Abbott, D.O. — ABFM Board-Certified Physician
★★★★★5.0 from 46 Google reviews
ABFM Board Certified Evidence-Based Care Personalized Treatment Plans
How It Works

The Same Active Ingredient, One Fewer Component

Xeomin (incobotulinumtoxinA) works through the same core mechanism as Botox and Dysport — relaxing the muscles responsible for expression lines — but it's manufactured without the accessory proteins that surround the active toxin in other formulations. Some patients are drawn to this “naked” formula specifically, including those who've developed resistance to other botulinum toxin products, since the theoretical risk of developing neutralizing antibodies may be lower without those additional proteins.

In terms of results, onset, and duration, Xeomin performs very similarly to Botox for most patients. The meaningful difference is in formulation, not typically in how the treatment feels or how long it lasts.

What to expect

A consultation to assess your muscle patterns and treatment area
Treatment itself typically takes 10–15 minutes
Minimal downtime — most patients return to normal activities immediately
Results visible within about 3–7 days
Full effect settles in by about 2 weeks
Results typically last 3–4 months
How We Approach It

A Good Option If You've Built Resistance to Other Products

Xeomin is worth discussing specifically if you feel like Botox or Dysport haven't worked as well over time, since developing some resistance to accessory proteins is a recognized (if uncommon) phenomenon. We'll talk through your treatment history and whether switching makes sense for you.

Physician Insight

"Most patients don't need to think about which neuromodulator formulation to choose. But for the ones who've noticed their results fading faster than they used to, Xeomin's simpler formula is a genuinely useful option to discuss."

Related Conditions

Xeomin is often compared with: Botox and Dysport. See also Injectables & Fillers and our full Med Spa menu.

What Patients Say
Common Questions

Xeomin FAQs

What patients ask most before their first appointment.

Xeomin is manufactured without the accessory proteins that surround the active toxin in Botox and Dysport. The active ingredient works the same basic way; the difference is in the surrounding formulation, which some patients specifically prefer.
It's worth a conversation. Developing some resistance to the accessory proteins in other formulations is a recognized possibility over years of treatment, and Xeomin's simpler formula is one option some patients find helps in that situation.
For most patients, yes — results typically last a similar 3 to 4 months. Individual results vary regardless of which product you use.
Get Started

Curious If Xeomin Is the Right Fit?

Book a consultation and we'll talk through your treatment history and whether Xeomin makes sense for you.